Spaces and ligaments
Right subphrenic space communicates with anterior and posterior subhepatic spaces and with pelvic peritoneal cavity via the right paracolic gutter
Morrison's pouch => posterior subhepaptic space
Left subphrenic space communicates with left subhepatic space, but not with right subhepatic space because of the falciform ligament
Lesser omentum is composed of gastrohepatic and hepatoduodenal ligaments
Separates the gastrohepatic recess of the left subphrenic space from lesser sac
Greater omentum
Retroperitoneal space is divided into:
Anterior pararenal space => pancreas, duodenal loop, ascending and descending portions of the colon
Perirenal space
Posterior perirenal space => contains fat
Pelvic compartments
Peritoneal => Pouch of Douglas (Cul de Sac) or rectovesical pouch
Retroperitoneal => Extraperitoneal space of the pelvis, which includes retropubic space of Retzius
Perineum => ischiorectal fossa
Ascites Fluid
Serous ascites => -10 to +10 HU
Exudative ascites => +15 HU
Acute blood => + 45 HU
Pseudomyxoma peritonei => gelatinous ascites from spread of mucin producing cells (scalloping of the liver)
Rupture of appendiceal mucocele
Intraperitoneal spread of mucinouls adenocarcinoma
Ovarian
Colol/rectum
Mucinous tumors
Pancreas
Ovary
Appendix
Urachus
Peritoneal carcinomatosis
Omental caking
Peritoneal metastases
Peritoneal mesothelioma
Retractile mesenteritis
Infiltrating soft tissue mass with calcifications and tethering of bowel loops
Desmoid tumors
Gardner syndrome
Low density cystic mesenteric masses
Treated lymphoma
Necrotic metastases
Mycobacterium
Whipple disease
Cavitary mesenteric lymph node syndrome
Complication of celiac disease
Calcifications
Vascular calcifications
Calcified lymph nodes
Gallstones or calcified gallbladder
Urinary calculi
Granulomas
Appendicoliths and enteroliths
Calcified adrenals
Pancreatic calcifications
Calcified cysts
Tumor calcifications
Soft tissue calcifications => hypercalcemia, old hematomas, injection granulomas, cysticercosis
Retroperitoneal fibrosis
Idiopathic in 2/3 of the cases
Methysergine (anti-migraine medication)
Metastatic foci which elicit fibrotic reaction
Inflammatory aneurysms
TB, syphillis, actinomycosis, fungi
Omental caking
Primary => mesothelioma
Peritoneal carcinomatosis
Ovary
Colon
Stomach
Pancreas
Uterus
Bladder
Omental torsion
Usually in the right abdomen
Epiploic appendigitis
Fatty mass with hyperattenuating rim
Usually adjacent to sigmoid
Fatty infiltration is best evaluated on non-contrast images. Spleen enhances 1-2 min before liver and may be transiently brighter than normal liver. Normal liver is same or higher density than the spleen on CT, and slightly hypoechoic to spleen and isoechoic or slightly hyperechoic to kidney on US. Liver is higher in SI compared to spleen on T1WI , and lower or same compared to spleen on T2WI.
Diffuse disease
Diffuse fatty infiltration
Focal fatty infiltration
Multifocal fatty infiltration
Focal sparing
Cirrhosis
Fatty infiltration and hepatomegaly (early)
Non-uniform attenuation and irregular fibrosis (late)
Irregular contour
Regenerating nodules
Decreased liver volume (chronic cirrhosis)
Accentuation of fissures
Ascites and portal hypertension
Portal hypertension
Portal vein thrombosis
Passive congestion
Iron deposition
Budd Chiari
Hemochromatosis
Liver, pancreas, heart
Hemosiderosis
Liver, spleen, bone marrow
Glycogen storage disease
Predisposes to multiple adenomas
Focal disease
Infection
Pyogenic abscess
Amebic cyst
Solitary cyst
Echinococcal cyst
Solitary mass with internal cysts
Candidiasis
Bull-eye lesions on sonography.
Cavernous hemangioma (most common focal hepatic mass)
Well-defined isodense to blood-filled spaces
Peripheral nodule-like enhancement, centripetal fill-in
Contrast enhancement for 20-30 min
Large lesion with areas of fibrosis, occasional calcifications
Red blood cell scintigraphy is usually diagnostic
Focal nodular hyperplasia
Hypodense, homogenous, homogenous enhancement, central scar (hyperintense on T2)
Central scar enhances late
Tc99mSC → normal (40%), increased (10%), cold defect (50%)
Multiple in 7% of cases
Hepatic adenoma
Hypodense heterogenous mass, hemorrhagic, heterogenous enhancement
Absence of uptake of Tc-99m SC
Multiple in 30% of cases
Can hemorrhage
Intracellular fat on in-phase/out-phase imaging
Biliary cystadenoma
Large septated cystic mass
Angiomyolipoma
Metastasis
Hepatoma (Hepatocellular carcinoma)
Types: Solitary (50%), Diffuse infiltrative (30%), Multinodular (20%)
Low density, enhances in arterial phase, areas of necrosis, calcifications in 25%
Fibrolamellar carcinoma => subtype of HCC
Well-defined hypodense mass, central low density scar (hypointense on T2), marked enhancement
DiffDx: Focal Nodular hyperplasia (central scar is hyperintense on T2)
Lymphoma
Multiple well defined hypodense nodules
Hepatoblastoma
Cystic masses
Simple hepatic cyst
Pyogenic abcess
Amebic abcess
Echinoccoccus cyst
Cystic/Necrotic liver tumors
Biliary hamartomas of the liver (Von Meyenburg complexes)
Cholangiocarcinoma
Primary sclerosing cholangitis
DiffDx: PBC, cholangiocarcinoma
Discontinous biliary dilatation
Associated with IBD, pancreatitis, retroperitoneal and mediastinal finrosis
Complications: cirrhosis and cholangiocarcinoma
AIDS cholangiopathy
Indistinguishable from PSC
Oriental cholangiohepatitis
Strictures, dilatations, stones, straight rigid intrahepatic ducts
Primary biliary cirrhosis
Small bile ducts are involved
Crowding and deformity of bile ducts
Bacterial cholangitis
Caroli’s disease => saccular ectasia of intrahepatic ducts
Associated with medullary sponge kidney and ARPKD
Choledochal cyst
Classification of congenital cysts
Focal saccular or fusiform dilatation of CBD
True diverticuli of CBD
Cholledochoceles at the intraduodenal portion of CBD
Multiple intrahepatic and extrahepatic cysts
Caroli's disease
Segmental saccular dilatations in the non-obstructed intrahepatic ductal system
Stasis with resultant predisposition to infection and stone formation
Increased risk of cholangiocarcinoma
Renal tubular exctasia and renal cystic disease are seen in 80% of cases
May need luminal contrast studies to differentiate from polycystic disease
Biliary obstruction
Stones
Sphincter of Oddi spasm
Cholangiocarcinoma
Ampullary carcinoma
Pancreatic carcinoma
Biliary papillomatosis
Gallbladder
Anatomy
Phrygian cap => fold or septation near the gallbladder fundus.
Ectopic gallbladder
Herniation into the lesser sac is possible
Duplications
Gallstones
Cholesterol 80%
Sufficiently calcified to be seen on plain films 15%
Acute cholecystitis
Porcelain gallbladder
Gallbladder carcinoma develops in 20%-30% of patients with porcelain gallbladder.
Gallbladder carcinoma
Mirizzi's syndrome => biliary obstruction from stone in cystic duct eroding into the CBD and causing inflammation which obstructs CBD
Thick GBW
Cholecystitis (acute or chronic)
Hepatitis
Portal venous HTN and CHF
AIDS
Hypoalbunemia
GB carcinoma
Adenomyomatosis
Hyperplastic changes in the mucosa and muscularis with resultant outpouchings of the mucosa into or through muscularis to form Rokitansky-Aschoff sinuses
Cholesterolosis
Cholesterol polyps
Strawberry gallbladder is diffuse
Most common metastatic lesion is melanoma
Gallstone ileus
Fistula
Gallbladder to duodenum (obstruction at the ileocecal valve)
Gallbladder to hepatic flexure (no obtruction)
Gallbladder to stomach (pyloric obstruction is possible)
Gallbladder varices
Emphysematous cholecystitis
Dirty shadowing
Anomalies
Accessory spleen
Wandering spleen
Splenic regeneration
Splenomegaly
Size greater than 12 cm
Extension below costal margin
Diffuse disease
Gamna-Gandy Bodies (siderotic nodules) => small splenic hemorrhages caused by portal HTN
Lymphoma
Sarcoidosis
Multiple tiny hypoattenuating splenic lesions
Cystic lesions
Post-traumatic (false cysts)
Congenital epidermoid cysts (true cysts)
Echinococcal cysts
Pancreatic pseudocysts via dissection
Abcesses
Bacterial
Microabcesses – usually in immunocompromised
Fungi (Candida, Aspergillus, Cryptococcus)
TB
PCP
CMV
Solid lesions
Hemangioma
Inflammatory pseudotumor
Hamartoma
Infarction
Lymphoma
Metastases
Most commonly melanoma, breast, ovary, lung
Angiosarcomas
Hematoma
Dense atrophic spleen
Autosplenectomy from sickle cell disease
Thorium dioxide exposure
Congenital
Pancreas divisum
Normally dorsal duct (tail and body) and ventral duct (head) fuse to form Wirsung duct which drains into major papilla. Remaining portion of dorsal duct (Santorini) drains into more proximal minor papilla
In pancreas divisum, dorsal and ventral ducts never fuse resulting in dorsal duct (Santorini) draining most of pancreas via minor papilla
On axial CT in pancreas divisum, dorsal duct appears ventral, but drains most of the pancreas
Annular pancreas
Pancreatic duct encircles endoscope or duodenum on ERCP
Duodenal narrowing
Pancreatic tissue encircles duodenum on CT
Pancreatitis
Acute pancreatitis complications:
Phlegmon
Fluid collections
Pseudocyst (clearly identifiable fibrous capsule)
Necrosis
Abcess
Hemorrhage
Pseudoaneurysm
Thrombosis
Ascites
Chronic pancreatitis complications
Dilation of pancreatic duct, dilations of biliary duct
Atrophy
Calcifications
Fluid collections
Focal enlargement
Fascial thickening and stranding
Neoplasms
Pancreatic ductal adenocarcinoma
Hypovascular
Encases vessels
Rarely calcifies
Ductal dilatation is usually present
Lymphoma
Islet cell tumors
Hypervascular
Does not encase vessels
Calcifies
Solid and papillary epithelial tumor
Usually found in young women of African descent
Acinar cell carcinoma
Usually found in older men
Large size
Metastases
Renal cell and melanoma are most common
Local spread from kidney, stomach, or colon (may be hypervascular)
Hematogenous spread from breast, lung, melanoma
Lymphoma, leukemia
Local spread from adjacent organs
Cystic lesions
Cystic tumors
Serous cystadenoma (young female)
Usually more than 6 small cysts (< 2cm)
Intraductal pancreatic mucinous neoplasms
Ducts are usually dilated by mucin
Filling defects maybe visible
Mucinous cystic neoplasm
Most commonly found in pancreatic tail
Usually less than 6 large cysts (>2cm)
Microcystic adenomas
Pseudocyst
Abscess
True pancreatic cyst
vHL
Trauma
Fatty pancreas
CF
Tumors
RCC
Oncocytoma
Transitional cell carcinoma
Angiomyolipoma (tuberous sclerosis)
Renal lymphoma
Metastases
Cystic disease
Simple cyst (-10 HU to +15 HU)
Complicated cyst
Indeterminate
Renal abcess
RCC
Multilocular cystic neproma
Mutliple renal cysts
Multiple simple cysts
ADPD
Multicystic dysplastic kidney
von Hippel-Lindau disease
TS
Long term haemodialysis
Stones
Infection
Acute bacterial infection
Acute pyelonephritis
Lobar nephronia
Abscess
Emphysematous pyelonephritis
Pyonephrosis
Chronic infection
TB
Xantogranulomatous pyelonephritis
Esophagitis - inflammation/ulceration
Reflux
Barret's
Infectious
Candida => small mucosal nodules, which occur in longitudical columns - plaquelike
DiffDx: reflux and glycogenic acanthosis
Herpes => multiple discrete ulcers, normal mucosa in between ulcers
CMV/HIV => large flat plaques
TB
Drug induced
Crohn esophagitis
Motility
Cricopharyngeal achalasia
Esophageal achalasia => disease of myenteric plexus
Peristalsis is decreased or absent
LES fails to relax
Chaga's disease => destruction of Ganglion cells by Trypanosoma cruzi
Diffuse esophageal spasm
Neuromuscular disorders
CVA most common
Scleroderma => smooth muscle replaced by fibrous tissue
Rings
A-ring
Muscular ring at the superior aspect of the esophageal vestibule
B-ring
Mucosal ring at the inferior aspect of the esophageal vestibule
If less than 13 mm => Schatzki ring
Z-line is the squamcolumnar junction line and may not correspond to the B-ring.
Strictures
Enlarged esophageal folds
Varices
Uphill from portal hypertension => predominantly inferior location
Downhill from SVC obstruction => predominantly superior location
Lymphoma
Varicoid carcinoma
Masses/nodules
Ectopic gastric mucosa
Varices
Foreign body
Mucosal edema from reflux
Duplication cyst
Glycogenic acanthosis => focal deposits of glycogen
Pemphigoid and epidermolysis bullosa => subepidermal bullae or blebs
Cowden's syndrome => diffuse mucosal nodularity from hamartomas
Leukoplakia => hyperplasia of squamous epithelium
Neoplastic
GIST
In esophagus, the leiomyomas or more common
Inflammatory esophagogastric tumor
Fibroepithelial or fibrovascular polyp
May regurgitate into the pharynx
Adenoma
Carcinomas
90% are squamous cell carcinomas
Superficial spreading carcinoma
GIST
Metastases
Lymphomas
Spindle cell
Kaposi's sarcoma
Granular cell tumors
Outpouchings
Killian-Jamieson => Lateral pharyngeal outpouchings => common in wind players
Zenker's diverticulum => Killian dehiscence between circular and oblique fibers of the posterior aspect of cricopharyngeus
Midesophageal diverticula
Pulsion => from disordered peristalsis
Traction => from fibrous inflammatory reactions of adjacent lymph nodes
Epinephric diverticula
Usually of pulsion type in patients with motility disorders
Sacculations from healing of ulcerations
Foregut duplication cysts or acquired retention cysts
Intramural pseudodiverticula
Flask shaped
Associated with esophageal strictures/malignancies
Webs
Plummer-Vinson syndrome => esophageal webs, dysphagia, iron-deficiency anemia
Hernias
Sliding hiatal hernia
Paraesophageal hiatal hernia
Mixed hiatal hernia
Rupture
Boerhaave's syndrome => rupture
Mallory-Weiss tear => mucosa only
Can be normal
Fundus => 1 cm
Antrum => 5 mm
Gastritis (H.pylori)
Peptic ulcer disease
Menetrier disease
Zollinger-Ellison syndrome
Metastases
Carcinoma
Lymphoma
Varices
Ulcerations
Ulceration found in the fundus may be malignant because benign ulcers are uncommon in this location
Both benign and malignant ulcers are most common in the antrum
Carman meniscus sign
Compressed lesser curvature demonstrates convex barium trapped by heaped up mucosa
Kirkland complex => heaped up mucosa
Focal filling defects thickening (GAL BMP LP)
GIST (60-70% of GISTs occur in the stomach)
Arises either from common precursor cell to Cajal cells (intestinal pacemaker cell) and smooth muscle cells or from Cajal cells
Adenocarcinoma
Four types
Polypoid
Ulcerative
Scirrhous => linitis plastica
Superficial spreading => nodular thickening or superficial mucosal ulceration
Lymphoma
Bezoar
Metastases
Pancreatic rest
Lipoma
Polyps
Bowler hat sign
Mexican hat sign
Three types
Hyperplastic polyps
Adenomatous polyps
Hamartomatous polyps
Kaposi's sarcoma
Varices
Stomach and esophageal varices result from portal heypretension
Stomach onlyl varices result from splenic vein thrombosis
Extrinsic compression
Caustic stricture
Granulomatous disease (Crohn, sarcoid, TB, syphilis, eosinophilic gastroenteritis)
Peptic scarring
Metastases (linitis plastica)
Usually from breast carcinoma
Scirous adenocarcinoma
Lymphoma
Filling defects
Tumors
Adenocarcinoma
Metstases
Lymphoma
Duodenal adenoma
Leiomyoma/Leiomyosarcoma
Lipoma
Lymphoid hyperplasia
Brunner's gland hyperplasia/adenoma
Heterotopic gastric mucosa
Ectopic pancreas
Extrinsic mass
Thickened folds
Can be normal
Duodenitis
Pancreatitis/cholecystitis
Crohn's disease
Parasites
Giardia lamblia
Lymphoma
Intramural hemorhhage
Thick folds resemble stack of coins
Ulcers
H. pylori infection
Zollinger-Ellison syndrome
Flexural pseudotumors
Filling defect at the flexure at the apex of the bulb
Diverticula
Can be intraluminal
Narrowing
Annular pancreas
Neoplasms
Postbulbar ulcer
Extrinsic
Obstruction
Strangualtion obstruction
Closed loop obstruction
Intussusception
Filling defects
Carcinoid => sunburst pattern of radiating mesenteric fibrosis
Adenocarcinoma
Lymphoma
Most cases are Non-Hodgkins
Burkitt's lymphoma
AIDS related lymphoma
Nodular lymphoid hyperplasia
Metastasis
Kaposi's sarcoma
Leiomyoma and leiomyosarcoma
Adenoma
Lipoma
Hemangioma
Polyposis syndromes
Acariasis
Diffuse small bowel disease
Uniform thickening => infiltration by fluid
Irregular thickening => infiltration by cells or non-fliud material
Dilatation
Thickened folds
Regular => edema or hemorrhage
Irregular
Focal small bowel disease
Proximal dilatation
Sprue
Scleroderma
Erosions and ulcerations
Crohn's disease
Yersenia enterocolitis
Behcet's disease
TB
Diverticula
Meckel's diverticula
Pseudodiverticula => outpouchings of antimesenteric border that result from disease of the small bowel
Circumferential small bowel wall thickening (HIL)
Hematoma
Ischemia (if diffuse)
Lymphoma
Mesenteric masses
Lymphoma
Mesenteric desmoid
Mesenteric cysts
GI duplication cysts
Mesenteric teratomas
Obstruction
Sigmoid volvulus
Cecal volvulus
Fecal impaction
Adenocarcinoma
Polyps
Four types
Hyperplastic
Adenomatous
Hamartomatous
Inflammatory
Familial Adenomatous Polyposis Syndromes
Gardner's
Turcot's
Hamartomatous Polyposis Syndromes
Peutz-Jeghers
Cowden's
Cronkite-Canada
Lymphoid hyperplasia
Lymphoma
Leiomyoma and Leiomyosarcoma
Lipoma
Extrinsic masses
Endometriosis
Metastastases
Colitis
Diverticulitis
Crohn's disease
Amebiasis
Appendicitis
Actinomycosis
TB
Colonic wall thickening (PIIL)
Pseudomembranous colitis
Ischemic colitis
Infectious colitis
Lymphoma
Sacculations
Scleroderma
Multiple intusseseptions
Melanoma metastasis
Rectal thickening
Lymphoma
UC
Cause of toxic megacolon in 75% of cases
Fat in bowel wall
Crohn's
Comb sign => parallel vascular engorgement of the vessels supplying the affected segment (1)
Creeping fat around terminal ileum
Crohn disease is associated with oxalate renal stones, gallstones, fusion of SI joints.
Appendicitis
Primary findings (1)
6-10 mm => equivocal or suggestive
>10 mm => nearly diagnostic
Wall thickening > 3mm
Hyperenhancment
Wall stratification
Secondary findings (1)
Appendicolith
Regional fat stranding
Thickened lateral conal fascia
Cecal or ileal wall thickening
Reactive regional lymph nodes
Phegmon vs. abcess
Phlegmon > 20 HU
Abcess < 20 HU (If more than 3 cm, generally requires drainage)
Apendiceal tumors
Carcinoid
Adenomas
Adenocarcinomas
Grade 1 - Subcapsular hematoma less than 1 cm in maximal thickness, capsular avulsion, superficial parenchymal laceration less than 1 cm deep, and isolated periportal blood tracking
Grade 2 - Parenchymal laceration 1-3 cm deep and parenchymal/subcapsular hematomas 1-3 cm thick
Grade 3 - Parenchymal laceration more than 3 cm deep and parenchymal or subcapsular hematoma more than 3 cm in diameter
Grade 4 - Parenchymal/subcapsular hematoma more than 10 cm in diameter, lobar destruction, or devascularization
Grade 5 - Global destruction or devascularization of the liver
Grade 6 - Hepatic avulsion
CT signs
Free intraperitoneal fluid without evidence of solid organ injury
Free air
Bowel wall edema
Associated with Chance fracture's in seat belt injury
Renovascular injury
Contusion
Subcapsular hematoma
Renal laceration/fracture
References